traqx

Cleanroom · Annex 1

Cleanroom evidence that carries through the cycle.

traqx links classification, monitoring, deviations and requalification along your cleanroom SOPs.

Relevant to EU-GMP Annex 1 and qualification evidence.

  • Bring CCS and evidence together visibly.
  • Stop reconstructing status again and again.
  • The decision stays a human responsibility.

The full platform

Annex 1ISO 14644

Cleanroom lifecycleEU-GMP Annex 1 (2022)

CCS EVIDENCE SPINE ANNEX 1 · ISO 14644-1 Grade A Grade B particle · viable · surface · personnel action limit exceeded Classification Qualification Monitoring CCS CAPA · open QA-REVIEW human decides accept · revise AUDIT-TRAIL source linked · review recorded · open item tracked · who · when

Room, class & scope captured · structure confirmed by a human

Why qualification status trembles before audits

It's not the qualification that's missing. It's the evidence logic.

A room is qualified — but why it is, is spread across classification reports, monitoring data, deviations, trends and SOPs. Before an inspection this rationale often has to be laboriously reassembled. The more rooms, classes and requalification cycles, the harder it becomes to hold a consistent, robust record.

01

The evidence is scattered, not linked

Classification, monitoring, deviations and SOPs live in separate repositories. Which evidence exactly supports the status of a room is not apparent at first glance.

02

Before the audit, it's reconstructed instead of evidenced

When the inspector asks why a room is qualified, the search begins: reports, trends and deviations are assembled by hand into a rationale — late and under pressure.

03

Open items vanish between cycles

Between qualification and requalification, open items, trend anomalies and due actions are easily lost — until they show up as a gap in the audit.

How traqx models your cleanroom qualification

traqx structures qualification logic, evidence and open items — along your cleanroom SOPs.

traqx uses your cleanroom SOPs, monitoring requirements and source spaces to pre-structure qualification logic, make evidence links visible and keep review decisions traceable. The core principle always stays the same: Policy → SOP → Template. No templates of your own yet? You start with our best-practice templates. Generate · Verify · Monitor, from classification to the audit trail.

Step 01 Capture room, class, scope & qualification status traqx captures room, cleanroom class, qualification scope and current status in structured form — the basis against which every further piece of evidence is linked. You confirm what holds. Structure from versioned templates, confirmed by a human
Step 02 Connect SOPs, plans & monitoring evidence Relevant SOPs, qualification plans and monitoring evidence are connected to the room — every link stays source-bound and clickably traceable, not freely asserted. Source-bound, limited to your approved pool
Step 03 Prepare qualification or requalification structure From the connected requirements traqx pre-structures the qualification or requalification logic — consistent with the source, not reinvented. Every block is a suggestion, until you accept, change or reject it. A suggestion stays a suggestion until your approval
Step 04 Link evidence, deviations & open items Evidence, deviations, trends and open items are linked with the qualification logic. Every statement of regulatory relevance ends on a clickable source — an invented citation fails deterministically and is marked as unverified. Deterministic citation check: pass / fail
Step 05 Surface review questions & responsibilities Open review questions and responsibilities are kept visible — who closes which gap before an inspection asks about it. Every acceptance or rejection is an attributed, audited decision. Every approval attributed · rejection requiring a rationale
throughout Hold an audit trail for changes & approvals Across all steps the audit trail records: who, what, when, on what basis. The change history is at the database level append-only — it can be neither changed nor deleted. Change history append-only (database trigger)

Why this holds up in an audit

The AI structures. You own it.

The AI output is never silently written into a validated dataset. Until you approve it, every evidence link stays a suggestion — and only your confirmation makes the qualification status defensible. Classification and requalification decision remain your regulated responsibility.

Generate A suggestion stays a suggestion AI values live as pending suggestions on the evidence they belong to. The stored qualification status stays unchanged until a human acts — no room counts automatically as qualified.
Verify Approval with mandatory rationale Every acceptance or rejection of evidence is an attributed, audited decision. A rejection marked as requiring a rationale demands a typed reason — the reason is recorded with the decision.
Monitor Source-bound, not freely invented Retrieval reach is limited to your approved source pool — classification reports, monitoring data, SOPs. Every citation is checked deterministically against this pool; an invented source is surfaced as a warning, not output as truth.

By construction

What a cleanroom qualification structurally safeguards.

Every piece of evidence

source-bound

From classification to monitoring evidence, every piece of evidence carries its source — clickably traceable, by a human confirmed. Less laborious reconstruction before the audit, more consistent evidence logic.

Status evidence

linked through

The qualification status of each room is linked with the evidence that supports it — the rationale is created with, instead of being assembled before the inspection. Gaps become visible earlier.

0

silent AI writes

No suggestion lands without human approval in the qualification record. By construction — not by discipline. So you go into requalification and inspection better prepared.

Cleanroom qualification is available today as soon as your customer-specific cleanroom and monitoring documents are in place. traqx is not a certification and not a guarantee — classification and requalification decision remain your regulated responsibility. We publish real time or cost effects only with robust pilot or case-study data.

Questions from practice

Common questions on cleanroom qualification

What does EU GMP Annex 1 require for cleanroom qualification?

Annex 1 (2022 revision) requires an overarching contamination control strategy, qualification of cleanrooms by grade, ongoing environmental monitoring and documented requalification. The common thread: contamination control must be evidencable as a complete system, not a collection of isolated records.

What is a Contamination Control Strategy (CCS)?

A documented overall concept that connects all technical and organisational contamination controls and evidences their effectiveness — from facility design through personnel flow to monitoring. The CCS is the document inspectors use to read the maturity of your contamination management.

How often must a cleanroom be requalified?

Annex 1 sets maximum intervals of six months for grades A and B and twelve months for grades C and D — shorter cycles follow from risk, for example after changes or notable monitoring trends. Annex 1 and your documented risk assessment govern.

How does AI help with Annex 1 documentation?

It drafts qualification and monitoring reports with source binding to CCS, measurement data and specifications — consistent across rooms and periods. Assessment and approval stay with QA; the audit trail connects measurement, statement and signature.

More disciplines

One platform, many use cases.

Same trust architecture — sources first, AI as a suggestion, human decides, audit trail stays — across every GxP discipline.

Security & standards · built for traceable evidence

Made in Germany GDPR-compliant · EU-hosted No model training on your data
Built forGAMP 5EU-GMP Annex 1121 CFR Part 11ALCOA+
MembershipsISPEPDAGQMA

Founded by CSV experts with 15+ years of domain expertise

Live demo · 1 real cleanroom · clearly scoped

Start with one room.

Bring a real cleanroom qualification along to the demo — one room, one class, exactly the evidence logic whose reconstruction holds you back before every audit. First structured drafts appear early in the first process; we set concrete time targets together before the start.

No sales pitch — a short conversation around your concrete cleanroom scope. We define success criteria in writing before the start; the documented assessment is yours even if you say no afterwards. EU-hosted, no model training, source room deleted on request with evidence.

We take a full 30 minutes per demo · slots in order of arrival